产品货号：
Z17441
中文名称：
GLI1抗体
英文名称：
Anti-GLI1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GLI1 Antibody |
| 指标别名 | GLI family zinc finger 1;GLI;PAPA8;PPD1;GLI1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,IF |
| 基因名称 | GLI1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human GLi1 recombinant protein (Position:Q768-A1106).Human GLi1 shares 79% amino acid (aa) sequence identity with mouse GLi1. |
| 实际分子量 | 118KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | GLI1,also known as GLI,is a protein originally isolated in human glioblastoma.The protein is encoded by GLI1 gene.It is mapped to 12q13.3.This gene is a member of a select group of cellular genes that are genetically altered in primary human tumors.GLI1 encodes a member of the GLI-Kruppel family of zinc finger proteins in the final steps of Hedgehog signaling in normal development and disease.The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation.The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop.Beside,various upstream patterning signals may be integrated by the Gli proteins to direct a coherent programme of neurogenesis. |
| Uniprot ID | P08151 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | GLI family zinc finger 1 |
| 蛋白名全称 | Zinc finger protein GLI1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 Immunofluorescence (IF) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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